Anemia in COPD

Alexandru Corlateanu, Serghei Covantev , Alexander G. Mathioudakis, Victor Botnaru


We read with interest the results by Rahimi-Rad MH et al. (1) suggesting that anemia is a predictor of mortality in chronic obstructive pulmonary disease (COPD). There is indeed increasingexpanding data highlighting the significant burden of anemia in patients with COPD. In our cohort, in Respiratory Department of State University of Medicine and Pharmacy “Nicolae Testemitanu”, Chisinau, Moldova, we found that anemia is also an independent risk factor for worsening dyspnea, reduced functional capacity and more comorbidities in COPD patients.


  1. Rahimi-Rad MH, Sadighi T, Rabieepour M, Dinparast R, RahimiRad S. Prevalence of anemia and its impact on mortality in patients with acute exacerbation of chronic obstructive pulmonary disease in a developing country setting. Pneumologia (Bucharest, Romania). 2015 Jul-Sep;64(3):27-30.
  2. Ergan B, Ergün R. Impact of anemia on short-term survival in severe COPD exacerbations: a cohort study. International Journal of Chronic Obstructive Pulmonary Disease. 2016;11(1):1775-83.
  3. Lomholt FK, Laulund AS, Bjarnason NH, Jorgensen HL, Godtfredsen NS. Meta-analysis of routine blood tests as predictors of mortality in COPD. European clinical respiratory journal. 2014;1.
  4. Nickol AH, Frise MC, Cheng HY, McGahey A, McFadyen BM, Harris-Wright T, et al. A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease. BMJ open. 2015;5(7):e007911.
  5. Boutou A, Hopkinson N, Polkey M. Anaemia in chronic obstructive pulmonary disease: an insight into its prevalence and pathophysiology. Clinical Science. 2015 2015-03-01 00:00:00;128(5):283-95

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